Levonorgestrel是一种口服有效的孕激素受体调节剂，具有诱导细胞凋亡的抗肿瘤活性。该药物在避孕方面应用广泛，并可与其他药物联用，同时在骨质疏松症和子宫平滑肌瘤的研究中显示出潜在价值
|
英文别名 (English Synonym) |
Levonorgestrel |
|
中文名称 (Chinese Name) |
左炔诺孕酮 |
|
靶点 (Target) |
Estrogen/progestogen Receptor |
|
通路 (Pathway) |
Endocrinology and Hormones |
|
CAS号 (CAS NO.) |
797-63-7 |
|
分子式 (Formula) |
C21H28O2 |
|
分子量 (Molecular Weight) |
312.45 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Xu Q, Qiu L, Zhu L, Luo L, Xu C. Levonorgestrel inhibits proliferation and induces apoptosis in uterine leiomyoma cells. Contraception. 2010 Sep;82(3):301-8. doi: 10.1016/j.contraception.2010.03.002. Epub 2010 Apr 13. PMID: 20705162. [2] Chen X, Hou X, Feng T, Han N, Wang J, Chang G. Anti-fertility effect of levonorgestrel and/or quinestrol on striped field mouse (Apodemus agrarius): evidence from both laboratory and field experiments. Integr Zool. 2022 Nov;17(6):1041-1052. doi: 10.1111/1749-4877.12568. Epub 2021 Jul 28. PMID: 34216194.
