18β-甘草次酸是中药甘草的主要活性成分，具有抗溃疡、抗炎和抗增殖等多种药理活性。
|
英文别名 (English Synonym) |
Enoxolone |
|
中文名称 (Chinese Name) |
甘草次酸；18β-甘草次酸 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
|
CAS号 (CAS NO.) |
471-53-4 |
|
分子式 (Formula) |
C30H46O4 |
|
分子量 (Molecular Weight) |
470.68 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Huang RY, Chu YL, Huang QC, Chen XM, Jiang ZB, Zhang X, Zeng X. 18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. PLoS One. 2014 Apr 2;9(4):e93690. doi: 10.1371/journal.pone.0093690. PMID: 24695790; PMCID: PMC3973544.[2]Yang G, Wang L, Yu X, Huang Y, Qu C, Zhang Z, Luo D, Lin J, Zhou L, Su Z, Zhang X, Chen H. Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats. Evid Based Complement Alternat Med. 2017;2017:3470320. doi: 10.1155/2017/3470320. Epub 2017 May 9. PMID: 28572827; PMCID: PMC5440796.
