米托蒽醌二盐酸盐(Mitoxantrone 2HCl) 拓扑异构酶II抑制剂/PKC抑制剂|CAS 70476-82-3（53351ES）

Mitoxantrone dihydrochloride（又名米托蒽醌二盐酸盐, mitozantrone dihydrochloride; Mitoxantrone 2HCl; NSC-301739 dihydrochloride; NSC301739 2HCl; NSC 301739 2HCl）是拓扑异构酶II抑制剂（topoisomerase II抑制剂）和蛋白激酶C抑制剂（PKC抑制剂），对PKC的IC₅₀值为8.5 μM。Mitoxantrone通过抑制DNA合成和细胞周期进程抑制白血病，可以诱导细胞凋亡，具有抗肿瘤活性。

参考文献

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冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。