Hydroxyfasudil羟基法舒地尔(HA-1100) ROCK1/2抑制剂|CAS 105628-72-6（53087ES）

Hydroxyfasudil (HA-1100, HA1100)，又称羟基法舒地尔，是fasudil hydrochloride的活性代谢物，是ATP竞争性、可逆的ROCK特异性抑制剂，作用于ROCK1/2的IC₅₀值分别为0.73 μM和0.72 μM。Hydroxyfasudil也能抑制中性粒细胞迁移，在体内表现出血管扩展剂的作用。

参考文献

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冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。