重组人胰岛素样生长因子-1(人IGF-1蛋白) Human IGF-1 Protein(Flag标签)(92201ES)
产品应用
Insulin-like Growth Factor I (IGF-I), is the dominant effector of Growth Hormone (GH) and is structurally homologous to Proinsulin. The 7.6 kDa mature IGFI is identical between isoforms and is generated by proteolytic removal of the N- and C-terminal regions. Mature human IGF-I shares 94% and 96% amino acid (aa) sequence identity with the mouse and rat orthologs, respectively. The body growth of animals is regulated by growth hormone and IGF-I. The classical theory of this regulation is that most IGF-I in the blood originates in the liver and that body growth is controlled by the concentration of IGF-I in the blood. Meanwhile, IGF-I has been shown to enhance neuronal survival and inhibit apoptosis. IGF-1 promote the proliferation of multiple myeloma (MM) cells and protect them against dexamethasone (Dex)-induced apoptosis.
高纯度、高活性、低内毒素、高批间一致性

-25 ~ -15℃保存,收到货之后有效期1年。
复溶后,无菌条件下,-85 ~ -65℃保存,3个月有效期。
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