Recombinant Mouse FGF-23 Protein(HEK293)_90482ES（90482ES）

FGF23 is predominantly secreted by osteocytes, with its secretion and cleavage tightly regulated by serum phosphate, 1,25-dihydroxyvitamin D (1,25D), and parathyroid hormone (PTH). It binds to FGF receptors in concert with the obligate co‑receptor α‑Klotho to promote phosphaturia and suppress renal 1,25D synthesis, thereby controlling systemic phosphorus balance. Disorders of FGF23 signaling lead to either hypophosphatemia (e.g., X-linked hypophosphatemia, XLH) or hyperphosphatemia (e.g., familial tumoral calcinosis).

高活性、高纯度、低内毒素、高稳定性

-25 ~ -15℃保存，收到货之日起有效期1年。复溶后，在4°C下可稳定保存1周。复溶后，-20℃~ -80℃下可稳定保存3-6个月。建议分装后于-20℃或-80℃冷冻保存以延长保质期。