分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
工具酶
抑制剂激活剂与常用试剂
仪器
耗材

Preparation of 2D ZIF-L and Its Antibacterial and Antifouling Properties

Jingyu Li, Yang Zhang, Haichao Zhao, Guoxin Sui

Journal:Nanomaterials

IF:5.3

DOI:10.3390/nano13010202

PMID:36616112

Published:2023-01-02

research field:细菌分泌系统细胞生物学传染病学微生物学分子致病机制

Abstract

The excessively leached metal ions from traditional metallic antimicrobial nanoparticles are harmful to biological and human tissues. Metal-organic frameworks (MOFs) coordinating bioactive metal ions to organic bridging ligands can potentially address this issue, avoiding the excessive leaching of metal ions and simultaneously exhibiting high effective antibacterial activities. Here, we report the preparation of a 2-dimensional leaves-like zeolitic imidazolate framework (ZIF-L) for potential antibacterial and anti-algae applications. The ZIF-L nanosheet exhibits complete inactivation ofEscherichia coli(phosphate buffer saline: 4 h) andBacillus subtilis(seawater: 0.5 h). The ZIF-L/epoxy composite has excellent antibacterial effect, poisoning effect and anti-adhesion effect on a variety of marine algae. It is worth noting that the removal rate (Escherichia coli) for ZIF/epoxy composite can be reached to 90.20% by only adding ZIF-L (0.25 wt%). This work will inspire researchers to develop more metal-organic frameworks materials for applications in the antibacterial and anti-algae fields.Keywords:ZIF-L;two dimensional;antibacterial;anti-algae

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