药物纳米棒介导的microRNA-101递送通过抑制自噬实现癌症自我增敏治疗
Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition
Xin Xiaofei, Du Xiaoqing, Xiao Qingqing, Azevedo Helena S., He Wei, Yin Lifang
Journal：Nano-Micro Letters
IF：9.04
DOI：10.1007/s40820-019-0310-0
PMID：34138035
Published：2019-09-25
research field：肿瘤学分子生物学药理学癌症生物学呼吸生物学纳米技术
Abstract
Nanosized cytotoxic drug could combat against the autophagy induced by the drug. The drug nanorods enabled efficient intracellular delivery of the nucleic acid and the resultant autophagy inhibition in vitro and in vivo, which in turn sensitized the cancer cells to the anti-tumor nanorods.
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